I am still experiencing symptoms with my antidepressant, what do you suggest?

Question

Hello, I am 50 years old and I am on Zoloft 25 mg since May 20 for anxiety disorder. Since then, I have been experiencing inner agitation, especially in the morning when I wake up, but it is similar to small panic attacks. I take Zoloft in the evening with dinner. I got the covid in January and the anxiety has increased a lot since then. I get exhausted at the slightest effort. My doctor is reluctant to increase the dose not knowing if the restlessness is a side effect. I have been feeling more anxious for the past few days and I don't go out for fear of not feeling well outside of my home. I am able to calm the stress and agitation with anxiolytics. I have also started psychotherapy and I am off work. What do you suggest? I'm a little desperate for help. Thank you for your help! I am also taking Estrace 0.5mg increased to 1mg for 6 weeks, and prometrium 100mg. Thank you very much, I will give myself time and accept my condition.

Naji-tom Samaha · Accepted Answer

Thank you for your question! I am reassured that you are receiving appropriate follow-up with your doctor and that you have begun psychotherapy. I am also reassured that you can use anxiolytics if needed, as long as they do not become chronic. The 25 mg dose is considered low. It is not often seen in practice. Most patients taking sertraline take higher doses. With reservations, the dose could be increased, but if it is not well tolerated, the dose can be decreased without problems. The 50mg dose is safe and well tolerated in most people Keep in mind that treating anxiety may sometimes require trial and error. Don't lose hope :) I invite you to discuss this with your doctor and/or pharmacist who will be able to follow up with you more closely I hope I've been helpful, don't hesitate if there's anything you need! Tom Samaha, pharmacist It made me happy, but you don't have to "accept your condition" if your quality of life is not satisfactory. There are options for you :)