Is it possible to split the dose of an antidepressant?
45-year-old woman5 years ago
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Hello,
I was wondering if it is possible to split the intake of an antidepressant if you have digestive problems?
I am currently taking fluoxetine 10 mg but it is quite possible that I will have to increase to 20 mg if 10 mg is not effective. However, I have taken antidepressants before and in the last few years, every time I increased the dose, I had heartaches or dizziness that was a bit stressful. Same thing if I eat heavy, rich or sweet food. It seems that my liver is tired...
So I wanted to know if 2 doses of 10 mg at 12 hours interval is equivalent in terms of efficiency... it seems to me that it would lighten my digestion...?
I thank you! :)
Melanie
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Wissam El-Chayeb · 5 years ago
Hi, You can do that from a pharmacokinetic point of view, but I wanted to mention that this side effect disappears with time and the body gets used to the higher dose.