Are there any contraindications to using Berberine with Sulfasalazine, Methotrexate and Synthroid?

Hello Ma'am,

There is no significant interaction between berberine and the medications described in your question.

I still recommend that you consult your doctor about taking this supplement at your next appointment. Indeed, it's not impossible that the supplement could change the dose of Synthroid you need to take.

Finally, if you see that the symptoms for which you are taking sulfasalazine and methotrexate become worse after taking berberine, it will be best to stop taking it.

Happy day,

Alexandre Chagnon, pharmacist